Neuroscience of Reward, Motivation, and Drive

Drive and motivation are central to affective neuroscience. Here, we describe the development of conceptualizations from early behaviorist theories to contemporary theories linking motivation closely to reward. Current experimental data suggest key roles of drive and motivation in the wanting, liking, and learning processes underlying the pleasure cycle supporting survival of individuals and species. In particular, the underlying functional neuroanatomy of drive and motivation is now becoming clearer in humans and other mammals, which provides hope for novel more effective interventions for the pervasive problems of drive and motivation in affective and addictive disorders.